Table 1. Sociodemographica and Clinical Characteristics of the 2247 Participants.
| Characteristic | No. (%) | ||
|---|---|---|---|
| Whole Cohort | Patients With Measured GFR <45 mL/min/1.73 m2 | Patients With Measured GFR ≥45 mL/min/1.73 m2 | |
| Participants | 2247 (100) | 991 (43.5) | 1256 (56.5) |
| Age, mean (SD), y | 71.5 (5.0) | 72.0 (5.5) | 70.5 (4.5) |
| Age group, y | |||
| 65-74 | 1710 (76.0) | 670 (67.5) | 1040 (83.0) |
| ≥75 | 537 (24.0) | 321 (32.5) | 216 (17.0) |
| Sex | |||
| Male | 1192 (53.0) | 541 (54.5) | 651 (52.0) |
| Female | 1055 (47.0) | 450 (45.5) | 605 (48.0) |
| Potential kidney donors | 16 (7.0) | 0 | 16 (13.0) |
| Weight, mean (SD), kg | 71.5 (18.0) | 73.0 (17.5) | 68.5 (16.5) |
| Height, mean (SD), cm | 163.5 (9.5) | 163.5 (9.5) | 163.0 (9.0) |
| BSA, mean (SD), m2 | 1.75 (0.20) | 1.78 (0.20) | 1.73 (0.20) |
| Mean BMI | 26.5 (5.5) | 27.3 (6.0) | 25.7 (5.0) |
| BMI ≥30 | 466 (21.0) | 257 (26.0) | 209 (16.5) |
| PCr, median (IQR), mg/dL | 1.28 (0.97-1.64) | 1.70 (1.39-2.11) | 1.04 (0.84-1.26) |
| Measured GFR in all participants, mean (SD), mL/min/1.73 m2 | 44.5 (21.0) | 31.0 (9.0) | 64.0 (15.5) |
| Albuminuria, median (IQR), mg/g | 45 (15-225) | 95 (30-500) | 25 (10-100) |
| Albuminuria, mg/g | |||
| UACR <30 | 940 (42.0) | 255 (26.0) | 685 (54.5) |
| UACR 30-300 | 827 (37.0) | 427 (43.0) | 400 (32.0) |
| UACR >300 | 480 (21.0) | 309 (31.0) | 171 (13.5) |
| UACR >3000b | 79 (3.5) | 59 (5.9) | 20 (1.6) |
| Patient with transplanted kidney | 311 (14.0) | 156 (16.0) | 155 (12.5) |
| Measured GFR in patients with transplanted kidney, mean (SD) | 47.0 (17.0) | 34.0 (7.5) | 60.0 (14.0) |
| Measured GFR in patients without transplant, mean (SD) | 49.5 (21.5) | 30.0 (9.5) | 65.0 (15.5) |
Abbreviations: BMI, body mass index, calculated as weight in kilograms divided by height in meters squared; BSA, body surface area; GFR, glomerular filtration rate; IQR, interquartile range; PCr, plasma creatinine; UACR, urinary albumin/creatinine ratio.
SI conversion factors: To convert plasma creatinine to micromoles per liter, multiply by 88.4. For an approximate conversion of albumin to creatinine ratio from milligrams per gram to milligrams per mole, divide by 10.
a
According to the French Haute Autorité de Santé,18 no correction factor for race and ethnicity in the CKD-EPI equation should be applied in the European population; therefore, no data concerning race and ethnicity were collected.
b
UACR >3000 mg/g defines nephrotic albuminuria.