Table 2.
Patients’ number with ventilator associated pneumonia due to colistin-resistant Acinetobacter baumannii-calcoaceticus complex | ||||||||
Isolate number of patients | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 |
Culture location | TA | BAL | TA | TA | TA | BAL | TA | BAL |
Phenotype of isolate | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 |
MIC of isolate | 8 | > 256 | 4 | 6 | 4 | > 256 | > 256 | > 256 |
Treatment | 1 | 1 | 1 | 1 | 2 | 3 | 2 | 2 |
Clinical response | Yes | Yes | No | No | Yes | Yes | No | Yes |
Laboratory response | Yes | Yes | No | Yes | Yes | Yes | Yes | Yes |
Radiological response | Yes | Yes | No | No | Yes | Yes | No | Yes |
Microbiological response | Yes | Yes | No | No | Yes | Yes | Yes | Yes |
VAP-related mortality | No | No | Yes | No | No | No | Yes | No |
Treatment 1: meropenem + colistin, Treatment 2: meropenem + ampicillin/sulbactam, Treatment 3: colistin + amikacin. MIC: Minimum inhibitory concentration; VAP: Ventilator-associated pneumonia; BAL: Bronchoalveolar lavage; TA: Tracheal aspirate.