. 2019 Apr 18;47(10):5260–5275. doi: 10.1093/nar/gkz254

Table 1.

Observed rate constants for opening (k_open or k_open,1, k_open,2) and closing (k_close) of eIF4A in the presence of different RNAs

RNA	k _open(,1) (s⁻¹)	k _open,2 (s⁻¹)	k _close (s⁻¹)
10mer	0.67		0.16
14mer	0.32		0.24
20mer	0.30		0.21
30mer	0.34		0.95
50mer	0.31		0.69

10/10mer	0.30 (33%)^a	5.8 (67%)^a	0.17
14/10mer	0.29 (43%)^a	6.1 (57%)^a	0.17
20/10mer	0.26 (44%)^a	4.4 (56%)^a	0.19
30/10mer	0.21 (48%)^a	0.86 (52%)^a	0.82
40/10mer	0.19 (42%)^a	0.72 (58%)^a	0.91
50/10mer	0.20 (18%)^a	0.59 (82%)^a	1.3

30/10mer	0.39^b		0.82
40/10mer	0.37^b		0.91
50/10mer	0.47^b		1.3

^aValues in brackets are the amplitudes of the slow and fast phases from double-exponential fits.

^bRate constant for opening from single-exponential analysis of the CDHs in the presence of 30/10mer, 40/10mer and 50/10mer RNAs.