. 2019 Apr 18;47(10):5260–5275. doi: 10.1093/nar/gkz254

Table 2.

Microscopic rate constants for opening (k_-1, k_-2) and closing (k₁, k₂) of eIF4A in the presence of double-stranded RNAs, and individual equilibrium constants K₁, and K₂. See Figure 7B and Supplementary Methods for the definitions of rate constants

RNA	k ₁ (s⁻¹)	k _-1 (s⁻¹)	K ₁	k ₂ (s⁻¹)	k _-2 (s⁻¹)	K ₂
10/10mer	0.024	0.30	0.18	0.15	5.8	0.025
14/10mer	0.031	0.29	0.17	0.14	6.1	0.023
20/10mer	0.049	0.26	0.24	0.14	4.4	0.032
30/10mer	0.22	0.21	1.5	0.60	0.86	0.70
40/10mer	0.39	0.19	1.9	0.52	0.72	0.73
50/10mer	0.35	0.20	2.6	0.95	0.59	1.6