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. 2019 Apr 24;47(10):4911–4926. doi: 10.1093/nar/gkz292

Figure 4.

Figure 4.

Splicing-associated HDAC-substrates. Comparison of results from three independent studies of splicing-associated proteins that are hyperacetylated with HDAC inhibitors treatment, or SIRT1 KO, are shown. SILAC data from Scholz et al. (97) of splicing-associated proteins that were hyperacetylated in HeLa cells due to treatment with HDAC inhibitors is shown in orange (upper circle). Data of such proteins from Sirt1 KO MEF cells are shown in purple (lower left) and blue (lower right) from Peng et al. (96), and Chen et al. (95) respectively.