. 2019 Apr 24;47(10):4911–4926. doi: 10.1093/nar/gkz292

Table 2.

Examples of cancer-associated non-histone substrates of HDACs. The RNA encoding these substrates are regulated by alternative splicing

Alternatively spliced non-histone HDAC substrate	HDAC
p53	HDAC1, SIRT1 (82–84)
STAT3	HDAC3 (152)
PPARA	SIRT1 (153)
CTTN	HDAC6 (154)
MLH1	HDAC6 (155)
MAX	Class I-IV (156)
PKM2	SIRT6 (157)
PFKFB3	Class III (158)
PTEN	HDAC6 (159)
HSP90	Class I-II (160)