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. 2019 Jun 4;2019(6):CD013346. doi: 10.1002/14651858.CD013346

Table 1.

Guideline recommendations for surveillance for hepatocellular carcinoma

GUIDELINE INDICATION TO SURVEILANCE TEST INTERVAL
American Association for the Study of Liver Disease (AASLD) (Heimbach 2018) Cirrhosis Abdominal ultrasound alone or plus AFP 6 months
European Association for the Study of the Liver with European Organization for Research and Treatment of Cancer (EASL‐EORTC) (EASL‐EORTC 2012; EASL 2018) Cirrhosis in Child Pugh stages A and B; cirrhosis in Child C stage awaiting liver transplantation; non‐cirrhotic hepatitis B virus (HBV) carriers with active hepatitis or family history of HCC; non‐cirrhotic chronic hepatitis C with advanced liver fibrosis stage 3 (F3) Abdominal ultrasound 6 months
3 to 4 months: people with a nodule less than 1 cm or after resection or loco‐regional therapies
Asian Pacific Association for the Study of the Liver (APASL) (Omata 2017) Cirrhosis and chronic HBV infection at risk of HCC Abdominal ultrasound with serum AFP 6 months

AFP: alpha‐fetoprotein; HCC: hepatocellular carcinoma