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. 2019 Mar 27;47(10):5114–5125. doi: 10.1093/nar/gkz182

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© The Author(s) 2019. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Profile of replication initiation activity along a representative homologous locus in human (top), mouse (middle) and chicken (bottom) genomes. (A) Number of SNS reads per 500 bp window in human chr17:73 000 600–73 550 600, mouse chr11:115 376 000–115 926 000, and chicken chr18:10 486 119–11 036 119 regions. (B) Number of SNS reads in 100 kb windows in a 10 Mb region centred on the region presented in (A). Vertical grey dotted lines represent detected origins, and several homologous genes are annotated with thick lines.