Table 1.

PLINK parameters for run of homozygosity (ROH) analysis

Parameter	Value	Definition
-homozyg-snp	50	Minimum number of SNP required to consider a ROH;
-homozyg-kb	300	Size (Kb) of the sliding window;
-homozyg-density	50	Minimum density required to consider a ROH;
-homozyg-gap	1000	Maximum size (Kb) between two SNP to be considered in the same ROH;
-homozyg-window-snp	50	Number of SNP present in the sliding window;
-homozyg-window-het	3	Number of heterozygous SNP allowed in a ROH;
-homozyg-window-missing	5	Number of missing calls allowed in a ROH;
-homozyg-window-threshold	0.05	Proportion of overlapping windows that must be called homozygous to define a given SNP as in a homozygous segment.