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. 2019 Jun 3;19:115. doi: 10.1186/s12906-019-2525-5

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Heparinized human blood biocompatibility (a), brine shrimp lethality bioassay (a6); HaCaT and HFF1 cells compatibility with gels (b and c). RBC morphology of heparinized blood incubated with AM (a1), AV (a2), AM+AV (a3), DW (a4) and SW (a5). a6 diagram shows the mortality percentages of brine shrimp (A. salina). 500 μg/mL was shown to be suitable for HaCaT and HFF1 cells in vitro (b and c)