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. 2019 Jun 3;19:115. doi: 10.1186/s12906-019-2525-5

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Evaluation of wound closure, measurement of wound contraction and re-epithelialization. a Macroscopic wound healing images of Wistar rats at day 0, 6, 12, 18, 24 and 30 which were treated with AM, AV, AM+AV gel or without any gel (control). b Clinical evaluation of wound healing regarding wound contraction in rats at day 6, 12, 18, 24 (b1) and (b2) (level of significant was set * P < 0.05, ** P < 0.01 and *** P < 0.001). c Epithelialization period in different groups (*P < 0.05, ** P < 0.01 and *** P < 0.001)