Table 1.

Histological scoring parameter of epithelialization, angiogenesis, granulation tissue formation, and inflammatory cells

Parameter/Score	0	1	2	3
Inflammatory cells	1–5 inflammatory cells per histological field	5–8 inflammatory cells per histological field	8–11 inflammatory cells per histological field	11–15 inflammatory cells per histological field
Epithelialization	Absence of epithelial proliferation in ≥70% of tissue	Incomplete epidermal organization in ≥50% of tissue	Moderate epithelial proliferation in ≥60% of tissue	Complete epidermal remodeling in ≥80% of tissue
Angiogenesis	Absence of angiogenesis including congestion and hemorrhage	2–4 vessel per site, congestion and hemorrhage	4–6 vessel per site, slight congestion	7–8 vessel per site vertically disposed towards the epithelial surface
Granulation Tissue	None, completely disorganized and distorted	Minimal/immature thin	Mild/moderately mature granule layer	Evident/ Thick, ≥80% organized