Table 4.
Summary of smoking outcome measure data
| Outcome | Control | Intervention | ||||
|---|---|---|---|---|---|---|
| n | Baseline rate | Rate at follow-up (95% CI) | n | Baseline rate | Rate at follow-up (95% CI) | |
| 4-week quitter (eCO or SC/SA verified) | 40 | NA | 5% (1 to 17%) | 40 | NA | 28% (16 to 43%) |
| 6-month quitter (RS6) | 40 | NA | 5% (1 to 17%) | 40 | NA | 15% (7 to 29%) |
| n | Baseline mean (SD) | Mean change from baseline to 6 months (SD; 95% CI) | n | Baseline mean (SD) | Mean change from baseline to 6 months (SD; 95% CI) | |
| eCO (ppm) | 29 | 17.1 (10.4) | − 5.8 (12.3; − 10.5 to − 1.1) | 29 | 22.0 (12.8) | − 12.0 (11.0; − 16.2 to − 7.9) |
| FTND | 29 | 4.6 (2.5) | − 1.6 (2.1; − 2.4 to − 0.8) | 29 | 4.6 (1.6) | − 1.9 (2.0; − 2.7 to − 1.2) |
| MPSS | 29 | 22.8 (7.5) | − 2.8 (8.3; − 6.0 to 0.3) | 29 | 21.8 (4.9) | − 2.8 (8.8; − 6.1 to 0.6) |
| SC (ng/ml) | 29 | 277.2 (131.5) | − 37.1 (133.4; − 90.0 to 15.7) | 29 | 326.3 (145.5) | − 62.2 (132.3; − 112.5 to − 11.8) |
| SA (ng/ml) | 29 | 0.8 (0.8) | 0.5 (2.3; − 0.5 to 1.4) | 29 | 1.2 (1.3) | − 0.4 (1.2; − 0.9 to 0.0) |
In line with recommendations for smoking cessation trials [4], participants with missing smoking outcome data (e.g. those not attending for review) were considered as continuing smokers or to have resumed smoking. Hence, the denominator for the 4-week and 6-month quitter outcome is the baseline number of participants (n = 40). For continuous variables, missing data were not imputed
eCO expired air carbon monoxide, RS6 Russell standard 6-month quitter, FTND Fagerstroms test of nicotine dependence, MPSS Mood and Physical Symptoms Scale, SC salivary cotinine, SA salivary anabasine, NA not applicable