Table 1.
Subject demographics and neuropsychological assessments
| SCD (n = 65) | NC (n = 73) | P value | |
|---|---|---|---|
| Age (years) | 65.85 (4.85) | 64.55 (5.52) | .147 |
| Education | 11.86 (2.70) | 11.68 (3.31) | .734 |
| Gender (male/female) | 23/42 | 38/35 | .138 |
| APOE ε4 (+/−)a | 16/48 | 14/56 | .443 |
| MMSE | 28.65 (1.23) | 28.79 (1.38) | .866 |
| MoCA-B | 25.25 (2.36) | 25.79 (2.48) | .338 |
| AVLT-IR | 6.50 (1.13) | 6.66 (1.68) | .432 |
| AVLT-DR | 6.57 (1.84) | 6.95 (2.20) | .166 |
| AVLT-R | 21.95 (1.74) | 22.56 (1.46) | .005 |
| STT-A | 63.49 (16.42) | 64.56 (22.94) | .112 |
| STT-B | 143.85 (37.44) | 139.22 (37.24) | .913 |
| AFT | 17.88 (4.28) | 18.81 (4.60) | .232 |
| BNT | 24.74 (2.45) | 25.26 (3.14) | .396 |
| GDS | 3.35 (3.16) | 1.89 (1.80) | .382 |
| HAMD | 5.66 (4.26) | 2.51 (2.64) | < .001 |
| HAMA | 6.34 (4.70) | 2.65 (2.43) | < .001 |
APOE apolipoprotein E, MMSE Mini-Mental State Examination, MOCA-B Montreal Cognitive Assessment Basic Version, AVLT-IR Auditory Verbal Learning Test-immediate recall, AVLT-DR Auditory Verbal Learning Test-delay recall, AVLT-R Auditory Verbal Learning Test-recognition, STT-A Shape Trails Test Part A, STT-B Shape Trails Test Parts B, AFT semantic fluency (animals), BNT Boston Naming Test, GDS Geriatric Depression Scale, HAMD Hamilton Depression Rating Scale, HAMA Hamilton Anxiety Rating Scale
aAPOE genotype results were included in SCD subjects (N = 64) and controls (N = 70)