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. 2019 Jun 3;17:186. doi: 10.1186/s12967-019-1923-2

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — The whole blood relative expression levels of four miRNAs examined by microarray and qRT-PCR are similar in patients with NPC. By taking the mean value of the miRNA expression levels examined by using the microarray (30 samples) and quantitative real-time reverse transcription polymerase chain reaction (qRT-PCR) (10 samples) (2^−ΔΔCt values) in HS samples as reference value respectively, the relative fold expression of miR-188-5p (a), miR-4790-3p (b), miR-3615 (c), and miR-5583-5p (d) examined by microarray and qRT-PCR in NPC samples were calculated based on the respective reference values and showed no significant differences (all P > 0.05), which indicated that the data obtained by the microarray is reliable