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Assessment of genetic variation determined by PGxSeq in 235 subjects. According to functional effect (a), allele frequency reported in ExAC database (b), number of exonic variants per target region (c), and gene (d). ‡ For UGT1A4, UGT1A6, UGT1A8, and UGT1A9, only SNVs located within the first exon were counted while shared exons were assessed only once with UGT1A1. ExAC, Exome Aggregation Consortium; MAF, minor allele frequency
