Fig. 1.

Overview of Hox protein binding in Kc167 cells. a Schematic of an adult Drosophila showing domains of deployment of the 8 Hox genes. b Representative genomic region showing scaled binding profiles of the 8 Hox proteins and the Hox cofactors Hth and Exd. The Exd profile shows the binding of Exd when expressed in association with Hth. The representative Input profile is from the Abd-B transfection (arbitrary scaling). c Venn diagram showing overlap analysis of binding regions (q value 1e−2) for selected Hox proteins Dfd, Ubx, and Abd-B. Number in brackets gives the number of non-overlapping regions as a percentage of the total number of regions for each protein. d Plots of Hox binding selectivity. For each Hox protein, binding regions (q value 1e−2) are classified according to the number of Hox proteins bound (see scale). Plotted on the left as frequencies and on the right normalized as percentages of total peak number for each Hox protein