Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Jun 3;10(6):433. doi: 10.1038/s41419-019-1637-7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 4 — a Localization of n384546 in B-CPAP and KTC-1 cells by fluorescent in situ hybridization. Nuclei are stained blue (DAPI) and n384546 is stained red. 18S is localized in the cytoplasm and U6 is localized in the nucleus. b The percentage of n384546, β-actin, and U6 in the cytoplasm and nucleus fraction of B-CPAP and KTC-1 cells was determined by qRT-PCR. c MiR-145-5p expression in 53 pair samples of PTC and adjacent normal tissues was determined by qRT-PCR. d Negative correlation between n384546 and miR-145-5p expression in PTC patients (Pearson Correlation Coefficient = −0.459, p < 0.01). e MiR-145-5p expression in Scrambled Gapmer or Gapmer-n384546 transfected B-CPAP and KTC-1 cells was determined by qRT-PCR. f Relative levels of miR-145-5p in normal thyroid cell Nthy-ori 3-1 and two types of PTC cells, B-CPAP and KTC-1 were determined by qRT-PCR. g The predicted binding sites and binding energy of miR-145-5p to the n384546 sequence. Data in (d) represent the mean ± SEM of three separate experiments. Data in (e) represent the mean ± SEM of four separate experiments. *p < 0.05, **p < 0.01 in paired Student’s t test (b) and independent Student’s t test (d, e)