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. 2019 Jun 3;9:8245. doi: 10.1038/s41598-019-44670-w

Table 4.

Functional annotation within the category of lipid metabolism.

Diseases or Functions Annotation p-value z-score Molecules # Molecules
Multibacillary concentration of lipid 5.5E-04 −2.2 C1QA,CES1,CYBB,CYP4F2,FABP5,JUN,P2RY13,PDK4,S100A12,S100A8,S100A9,STARD10 12
concentration of fatty acid 1.0E-02 −2.2 CES1,CYP4F2,P2RY13,PDK4,STARD10 5
concentration of triacylglycerol 5.2E-04 −0.9 C1QA,CES1,CYBB,FABP5,JUN,PDK4,STARD10 7
concentration of cholesterol 1.8E-03 −0.7 CES1,CYBB,FABP5,JUN,P2RY13,STARD10 6
fatty acid metabolism 7.1E-03 0.5 CES1,CYP4F2,FABP5,KLF5,PDK4,S100A12,S100A8,S100A9 8
efflux of cholesterol 1.1E-03 0.9 CES1,S100A12,S100A8,S100A9 4
transport of lipid 3.6E-03 1.5 CES1,FABP5,S100A12,S100A8,S100A9 5
Paucibacillary transport of lipid 2.9E-02 −0.1 CD14,CES1,FABP3,ITGB3 4
catabolism of lipid 1.7E-02 AKR1C3,CES1,PLA2G7 3
binding of lipopolysaccharide 3.0E-03 BPI,CD14 2
transmission of lipid 5.4E-03 CD14,CES1 2
hydrolysis of triacylglycerol 1.2E-02 FABP3,PLA2G7 2
oxidation of palmitic acid 2.2E-02 FABP3,PDK4 2
quantity of diacylglycerol 2.5E-02 CES1,PDK4 2
transport of fatty acid 4.0E-02 CES1,FABP3 2
Resilient concentration of lipid 3.5E-03 −1.9 CYBB,FABP3,HNF4A,OLR1,P2RY13,PTGS2,S100A9,STARD10 8
concentration of cholesterol 1.6E-04 −1.7 CYBB,HNF4A,OLR1,P2RY13,PTGS2,STARD10 6
synthesis of eicosanoid 3.2E-03 −1.2 HNF4A,KLF5,OLR1,PTGS2 4
fatty acid metabolism 1.9E-03 −1.0 ACSL6,FABP3,HNF4A,KLF5,OLR1,PTGS2,S100A9 7
concentration of fatty acid 1.5E-03 −0.5 FABP3,OLR1,P2RY13,PTGS2,STARD10 5
uptake of lipid 1.1E-03 0.0 A2M,FABP3,OLR1,THBS1 4
uptake of long chain fatty acid 3.1E-05 FABP3,OLR1,THBS1 3
homeostasis of phospholipid 2.7E-04 FABP3,HNF4A 2
uptake of palmitic acid 9.8E-04 FABP3,OLR1 2
homeostasis of lipid 1.4E-03 FABP3,HNF4A,PTGS2,STARD10 4
transport of long chain fatty acid 2.5E-03 ACSL6,FABP3 2