Fig. 8.

Knocking down exosomal miR-328 expression in M2 macrophages inhibits the progression of PF in vivo. a The degree of fibrosis and expression of α-SMA and Collagen I observed by Masson staining and IHC, respectively, in the antagomir NC-exo and antagomir miR-328-exo groups (400 × ). b MOD values of α-SMA and Collagen I. * p < 0.05 vs. the mimic NC-exo group. miR-328, microRNA-328; NC, negative control; and α-SMA, α-smooth muscle actin. The results were measurement data and were analyzed using an unpaired t test. The results are expressed as the mean ± standard deviation. The experiment was conducted in triplicate