Table 1.

CaMKK2 expression by molecular breast cancer subtypes

	Viennaa				RPCIb					Combinedc
CaMKK2	N	LA	LB	TN	N	LA	LB	TN	N	LA	LB	TN
Low	32	75%	9%	16%	54	65%	19%	16%	86	69%	15%	16%
High	15	40%	20%	40%	14	43%	7%	50%	29	41%	14%	45%
ORd		0.2	nd	ns		ns	nd	5.0		0.3	nd	4.1
p-valuee		0.0241	nd	ns		ns	nd	0.0129		0.0107	nd	0.0026

N  sample numbers, nd  not determined, ns  not significant

Immunohistochemical analysis of CaMKK2 expression in human breast cancer tissue microarrays, from two independent datasets (⁸ and Roswell Park Cancer Institute, RPCI). CaMKK2 expression was determined to be low (<2) or high (> = 2), and correlated with molecular subtypes: triple negative (TN), luminal A (LA), and luminal B (LB). Fisher’s exact test was used to determine p-values for the likelihood of association

^aVienna data set; 47 samples

^bRoswell Park Cancer Institute data set; 68 samples

^cVienna and RPCI combined

^d,eOdds ratio and associated p-value