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. 2019 Jun 3;9:8215. doi: 10.1038/s41598-019-44696-0

Figure 10.

Figure 10

Impact of flight condition on expression of crystallins in the network of proteins associated with ophthalmic disease as defined by Ingenuity Pathway Analysis (IPA, https://www.qiagenbioinformatics.com/products/ingenuitypathway-analysis). Red = up-regulated (p < 0.1). Grey = un-changed. Green = down-regulated (p < 0.1). This figure is generated with IPA software. —Direct interaction. ╌╌╌╌ Indirection interaction. → Activation, expression, location, modification, molecular cleavage, phosphorylation, protein-DNA interactions, protein-RNA interactions, regulation of binding, transcription. ◊ Enzyme. Inline graphic Ion Channel. A more detailed description of the network illustration (squares, circles, etc.) can be found at the Ingenuity Systems website. http://qiagen.force.com/KnowledgeBase/articles/Basic_Technical_Q_A/Legend.