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. 2019 Jun 4;9:8265. doi: 10.1038/s41598-019-44580-x

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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(a) Correlation chart of the let7 family members in whole blood. Correlation chart of the let7 family (b), miR-17 family (c), and miR-320 family members (d) in both whole blood and serum. The upper-right side shows the correlation coefficient and p-value for each pairwise correlation. The lower-left side show the distribution. b,c and d show the correlation for the miRNA that are expressed in both biofluids. Intra-blood correlations (black quadrants) and intra-serum correlations (grey quadrants) are reported. Outside the quadrants the pairwise inter-biofluids correlations.