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. 2019 Apr 15;216(6):1328–1344. doi: 10.1084/jem.20182002

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© 2019 Tuncel et al.

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Figure 8. — The expression of ST2 on T reg cells was age and Aire dependent. (A) Concentration of IL-33 protein in lysates from various tissues of perinatal and adult mice (n = 3 mice/group). (B) Frequency of ST2⁺ T reg cells in Aire^+/+ and Aire^−/− mice of various ages. Left: Representative flow-cytometric plots. Right: Summary data (n = 6–11 mice/group). Data are pooled from at least two independent experiments and show mean ± SD. Statistical analyses as in Fig. 1. *, P ≤ 0.05; **, P ≤ 0.01; ****, P ≤ 0.0001.