Table 2.
Representative list of bacteria with cancer immunogenic traits
| Bacteria | Immunogen(s)/ Immunogenic properties | Active against | Synthesizing gene(s) | Reference(s) |
|---|---|---|---|---|
| Clostridium novyi | Phospholipases | Sarcomas, gliomas, squamous and colon carcinomas | The phospholipase C gene (NT01CX0979) | (170, 173, 174) |
| Escherichia coli | Lipopolysaccharide | Colon and breast carcinomas | Lipid A, core polysaccharide, and O-antigen genes | (175, 176) |
| Mycobacterium bovis | α antigen | Cervical adenocarcinoma and bladder cancer | The α antigen gene | (177-179) |
| Streptococcus pyogenes | Emm55, speA, speB and speC | Pancreatic carcinoma and lymphosarcoma | speA, speB, speC, and Emm55 genes | (180-182) |
| Listeria monocytogenes | Listeriolysin O | Ovarian and breast carcinomas. | The hly gene | (171, 172, 183, 184) |
| Salmonella typhimurium | Lipopolysaccharide/ survival within macrophages | Colon carcinoma | Lipid A, core polysaccharide, and O-antigen genes; slyA, STM3120 and htrA genes | (16, 185) |