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. 2019 Apr 21;10(8):1846–1854. doi: 10.7150/jca.28809

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CDCA5 promoted tumorigenicity in vivo. A. Evaluation of CDCA5 knockdown in LM3 cells after transfection with CDCA5 shRNA by western blot. B. Evaluation of CDCA5 knockdown in LM3 cells after transfection with CDCA5 shRNA by RT-qPCR. C. Representative images of xenografts from CDCA5-knockdown group and control group. D. Tumor growth curve of CDCA5-knockdown LM3 cells in nude mice compared to control group. E. Tumor weight of CDCA5-knockdown xenografts decreased significantly compared to control group. F. More apoptotic cells were observed in CDCA5-knockdown xenografts compared to control group detected by TUNEL assays (400 ×).