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. 2019 Mar 3;10(7):1616–1621. doi: 10.7150/jca.28218

Figure 2.

Figure 2

Estrogen upregulates prohibitin expression and promotes endometrial cancer cell proliferation. (A, C) Estrogen upregulates prohibitin expression with a dose-dependent manner. (B, D) Estrogen upregulates prohibitin expression with a time cause. (E) Estrogen enhances endometrial cancer cell proliferation. (F) knockdown prohibitin attenuates estrogen-enhanced endometrial cancer cell proliferation. *, p<0.05 compared with the control group. a, represents a significant difference compared with siCon; b, compared with siCon plus estrogen treatment.