Table 1.

Clinicopathological variables and the expressions of c-Myb and COX-2 in patients with colorectal cancer

Characteristics	Total	Tumor c-Myb expression				Tumor COX-2 expression
	(n)	Elevated (n)	Decreased (n)	P-value		Elevated (n)	Decreased (n)	P-value
All cases	202	116	86			102	100
Age (years)				0.933				0.946
< 60	57	33	24			29	28
≥ 60	145	83	62			73	72
Gender				0.894				0.195
Female	88	51	37			49	39
Male	114	65	49			53	61
Tumor location				0.095				0.030
Right hemicolon	76	51	25			47	29
Left hemicolon	61	32	29			29	32
Rectum	65	33	32			26	39
Differentiation				0.067				0.150
Well-moderate	184	102	82			90	94
Poor	18	14	4			12	6
Tumor size (cm)				0.812				0.199
< 5	110	64	46			51	59
≥ 5	92	52	40			51	41
Depth of invasion				0.020				0.003
Tis - T2	23	8	15			5	18
T3 - T4	179	108	71			97	82
Lymph node involvement				0.062				0.292
N0	126	66	60			60	66
N1 - N2	76	50	26			42	34
Distant metastatic spread				0.092				0.370
Absence (M0)	191	107	84			95	96
Presence (M1)	11	9	2			7	4
TNM stage
0 - Ⅱ	122	62	60	0.019		56	66	0.107
Ⅲ - Ⅳ	80	54	26			46	34
5-Fu-based chemotherapy				0.654				0.481
Absence	100	59	41			53	47
Presence	102	57	45			49	53
KI-67 expression				0.409				0.153
< 50%	71	38	33			31	40
≥ 50%	131	78	53			71	60
P53 status				0.808		28	36	0.192
Negative	64	36	28			74	64
Positive	138	80	58
CEA status				0.569				0.778
Negative	101	56	45			50	51
Positive	101	60	41			52	49

Abbreviations: TNM, tumor node metastasis