Table 2.
Comparison of phylotype coverage and diversity estimation of the 16S rRNA gene libraries at 97% similarity from the sequencing analysis
| Group | Observed species | Good's coverage (%) | PD-whole tree | Richness estimator | Diversity index | ||||
|---|---|---|---|---|---|---|---|---|---|
| ACE | 95% CI | Chao 1 | 95% CI | Shannon | Simpson | ||||
| NSCLC | 531 | 99.50% | 54.56 | 659.08 | 621.15-697.00 | 652.43 | 614.26-690.61 | 5.50 | 0.92 |
| Healthy Controls | 510 | 99.50% | 53.08 | 633.62 | 614.87-652.36 | 642.99 | 620.09-665.88 | 5.65 | 0.94 |
1 The operational taxonomic units (OTUs) were defined with 97% similarity level. 2 The coverage percentage (Good's) and richness estimators (ACE and Chao1), and diversity indices (Shannon and Simpson) were calculated using the R software. CI, confidence interval.