Table 1.
Characteristics of the enrolled patients
| Variables | N (%) |
|---|---|
| Clinicopathologic factors | |
| Age (years) | |
| <65 | 82 (59.4) |
| ≥65 | 56 (40.6) |
| Sex | |
| Men | 79 (57.3) |
| Women | 59 (42.8) |
| ECOG-PS | |
| 0 | 8 (5.8) |
| 1 | 72 (52.2) |
| 2 | 58 (42.0) |
| Histologic type | |
| Squamous cell carcinoma | 29 (21.0) |
| Adenocarcinoma | 94 (68.1) |
| other | 15 (10.9) |
| Stage | |
| IIIB | 12 (8.7) |
| IV | 126 (91.3) |
| Number of organs with metastasis | |
| 0 | 12 (8.7) |
| 1 | 55 (39.9) |
| ≥2 | 71 (51.4) |
| Prior surgery | |
| No | 104 (75.4) |
| Yes | 34 (24.6) |
| Prior chemotherapy | |
| None | 60 (43.5) |
| 1st line | 38 (27.5) |
| 2nd line | 40 (29) |
| Prior radiotherapy | |
| No | 87 (63.0) |
| Yes | 51 (37.0) |
| Biologic markers | |
| CRP (mg/L) | 4.1 (0.1-252.8)* |
| ≤10 | 81 (58.7) |
| >10 | 57 (41.3) |
| Hemoglobin (g/dL) | 11.9 (6.8-14.9) |
| Men <13, women <12 | 80 (58.0) |
| Men ≥13, women ≥12 | 58 (42.0) |
| Ferritin (ng/mL) | 180.7 (6.2-3118.5) |
| Men ≤200, women ≤150 | 69 (50) |
| Men >200, women >150 | 69 (50) |
| Ferritin/hemoglobin | 14.5 (0.6-294.2) |
| <13 | 63 (45.7) |
| ≥13 | 75 (54.3) |
*Median (range). Abbreviations: CRP, C-reactive protein; ECOG-PS, Eastern Cooperative Oncology Group-performance status.