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. 2019 May 28;11:124. doi: 10.3389/fnagi.2019.00124

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Copyright © 2019 Sun, Ju, Wang, Zhang, Ding, Zhang, An, Sun, Li, Lu, Zhang and Chi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Decreased IL-10 concentrations in the serum and CSF of AD rats. IL-10 concentrations in the serum (A) and CSF (B) of the Control, AD7d and AD14d groups were determined with use of ELISA. n = 9 per group, mean ± standard deviation, ^∗∗∗P < 0.001 vs. Control group, ##P < 0.01, ###P < 0.001 vs. AD7d group. Positive correlations were obtained between serum IL-10 concentrations and percent of time in the target quadrant in the Control (C), AD7d (E), and AD14d (G) groups. Positive correlations were obtained between CSF IL-10 concentrations and percent of time in the target quadrant in the Control (D), AD7d (F), and AD14d (H) groups.