Table 2.
Relationship between preoperative LMR and clinicopathological features in patients with ESCC
| Characteristics | Total patients | LMR<3.17 (n=343 ) | LMR≥3.17 (n=337 ) | P value |
|---|---|---|---|---|
| Sex | Male | 321 | 261 | <0.001 |
| Female | 23 | 75 | ||
| Age at therapy initiation(years) | ≤60 | 148 | 164 | 0.130 |
| >60 | 196 | 172 | ||
| Pathology grade | Well differentiated | 28 | 21 | |
| middle differentiated | 228 | 221 | 0.539 | |
| Poorly differentiated | 81 | 85 | ||
| Undifferentiated | 0 | 2 | ||
| Missing | 7 | 7 | ||
| Depth of tumor | T1a-1b | 25 | 39 | |
| T2 | 67 | 64 | 0.151 | |
| T3 | 252 | 233 | ||
| Lymph node metastasis | N0 | 148 | 148 | |
| N1 | 102 | 111 | 0.307 | |
| N2 | 61 | 57 | ||
| N3 | 33 | 20 | ||
| Pathological stage | 1a-1b | 55 | 61 | |
| 2a-2b | 113 | 116 | 0.572 | |
| 3a-3c | 176 | 159 | ||
| Vessel invasive | Yes | 106 | 104 | 0.969 |
| No | 238 | 232 | ||
| Nerve infiltration | Yes | 127 | 127 | 0.813 |
| No | 217 | 209 | ||
| Treatment regimen | S | 234 | 227 | |
| S plus postoperative C | 81 | 74 | 0.641 | |
| S plus postoperative CRT | 29 | 35 | ||
| Hospital time after operation(days) | ≤14 | 264 | 273 | 0.149 |
| >14 | 80 | 63 |
Abbreviations: S: surgery; C: chemotherapy; CRT: chemoradiotherapy; LMR: lymphocyte to monocyte ratio.