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OS did not differ significantly between the RT and TKI group (35.4 vs 35.8 months, P=0.695)(A). The median time from brain metastases diagnosis to SST did not differ significantly between upfront RT group and TKI group (23.6 vs 18.9 months, P=0.862)(B). Abbreviation: OS, overall survival; RT, radiation therapy; TKI, tyrosine kinase inhibitors; SST, second-line systematic therapy.
