Table 1.
Itgam | Emr1 | Tnfα | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
CSAA | CDAA | CDAA +1%chol | CDAA +2%chol | CSAA | CDAA | CDAA +1%chol | CDAA +2%chol | CSAA | CDAA | CDAA +1%chol | CDAA +2%chol | |
4 weeks | 1.0 ± 0.2 | 17.4 ± 2.5 | 19.0 ± 2.8# | 22.9 ± 3.5# | 1.0 ± 0.1 | 3.1 ± 0.5# | 4.1 ± 0.5# | 3.9 ± 0.4# | 1.0 ± 0.1 | 4.6 ± 0.8# | 5.5 ± 0.9# | 5.3 ± 0.6# |
8 weeks | 0.9 ± 0.2 | 15.0 ± 2.7 | 43.2 ± 5.4#*∆ | 36.0 ± 3.6#* | 0.7 ± 0.1 | 2.7 ± 0.4# | 4.6 ± 0.3#* | 4.8 ± 0.4#* | 0.6 ± 0.2 | 3.5 ± 0.5# | 7.7 ± 0.6#* | 8.1 ± 0.6#* |
12 weeks | 1.7 ± 0.2 | 34.1 ± 4.7#∆$ | 45.2 ± 5.3#∆ | 52.3 ± 4.3#*∆ | 1.3 ± 0.1 | 3.3 ± 0.4# | 3.9 ± 0.3# | 4.8 ± 0.2# | 1.4 ± 0.4 | 7.9 ± 0.8#$ | 9.9 ± 1.0#∆ | 9.9 ± 0.7#∆ |
Acta2 | Pai1 | Ctgf | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
CSAA | CDAA | CDAA +1%chol | CDAA +2%chol | CSAA | CDAA | CDAA +1%chol | CDAA +2%chol | CSAA | CDAA | CDAA +1%chol | CDAA +2%chol | |
4 weeks | 1.0 ± 0.1 | 10.2 ± 1.4# | 10.2 ± 1.5# | 12.4 ± 1.2# | 1.0 ± 0.3 | 11.7 ± 2.4 | 15.9 ± 2.9 | 20.6 ± 2.6 | 1.0 ± 0.2 | 9.8 ± 1.6 | 21.6 ± 3.6 | 27.8 ± 3.3# |
8 weeks | 0.8 ± 0.2 | 7.9 ± 1.3 | 16.7 ± 1.9#* | 20.3 ± 3.0#* | 1.1 ± 0.4 | 10.3 ± 2.2 | 32.4 ± 6.4# | 36.2 ± 5.3# | 1.7 ± 0.6 | 16.1 ± 3.6 | 47.1 ± 7.7#*∆ | 51.1 ± 5.8#*∆ |
12 weeks | 1.6 ± 0.2 | 20.0 ± 2.9#∆$ | 19.5 ± 1.9#∆ | 20.1 ± 2.4# | 1.7 ± 0.7 | 32.9 ± 4.2# | 55.0 ± 14.4#∆ | 59.5 ± 13.0#∆ | 2.4 ± 0.4 | 58.3 ± 5.4#∆$ | 82.3 ± 6.3#*∆$ | 67.4 ± 7.6#∆ |
#P < 0.05 versus CSAA, *P < 0.05 versus CDAA, ∆P < 0.05 versus same diet at 4 weeks, $P < 0.05 versus same diet at 8 weeks