Table 6.
Predictive multivariate GLM for red versus other hair colours
| SNP ID | Function | MAF | Info score | Penetrance | Effect (OR) | P-value |
|---|---|---|---|---|---|---|
| rs1805007 | Missense | 1.03e-1 | 1 | R | 78.78 | <2.0e-16 |
| rs1805008 | Missense | 8.3e-2 | 1 | R | 35.32 | <2.0e-16 |
| rs1805009 | Missense | 2.78e-2 | 0.93 | R | 92.36 | <2.0e-16 |
| rs2228479 | Missense | 4.7e-3 | 1 | r | 0.80 | 2.6e-04 |
| rs312262906 | Frameshift | 9.7e-2 | 0.82 | R | 192.76 | <2.0e-16 |
| rs11547464 | Missense | 7.2e-3 | 1 | R | 46.93 | <2.0e-16 |
| rs885479 | Missense | 4.6e-2 | 1 | r | 0.78 | 6.1e-04 |
| rs1805006 | Missense | 1.22e-2 | 1 | R | 31.37 | <2.0e-16 |
| rs555179612 | Frameshift | 1.93e-3 | 1 | R | 225.45 | <2.0e-16 |
| rs76337330 | 5′ UTR | 4.9e-3 | 0.98 | ND | 0.63 | 1.03e-10 |
The designations R, high-penetrance, and r, low-penetrance, are based on previously reported associations with red hair. Effect size, here, OR > 1 denotes a positive association with red hair, and OR < 1 denotes a negative association with red hair. Info score is a measure of imputation quality.