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. 2017 Apr 27;10(3):169–177. doi: 10.1080/21541248.2017.1302550

Figure 2.

Figure 2.

Schematic representation of exocytotic pathway, which is modulated by Rab6 and Rab8. ARHGEF10 localized to Rab6- and Rab8-positive exocytotic vesicles, but not Rab6-positive Golgi apparatus and Rab8-positive tubular structure. It is possible that RhoA might contribute to the biogenesis of Rab8-positive tubular structure (j RhoA), the fission of exocytotic vesicles from Golgi apparatus (k RhoA), tethering of exocytotic vesicles to plasma membrane (l RhoA), mitotic-spindle formation (m RhoA) and ciliogenesis (m RhoA). Rab6-positive: blue, Rab8-positive: orange, ARHGEF10-positive: brown.