Fig 7. ArlRS–MgrA regulatory cascade controls adhesion to endothelium.

Adhesion of S. aureus GFP-expressing strains LAC (A) and MW2 (B) with the arlRS or mgrA deletions alone or with additional deletions of the giant surface proteins regulated by the ArlRS-MgrA cascade to cultured HUVEC human endothelial cell monolayer was tested in flow chamber at the physiological shear of 10 dyn/cm². N = 10 per group. *p<0.05, **p<0.01, ***p<0.001, ****p<0.0001, compared to WT. Data presented as mean ± SEM.