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. 2019 May 22;15(5):e1007800. doi: 10.1371/journal.ppat.1007800

Fig 9. Inhibition of ArlRS signaling with biochanin A decreases clumping and adhesion.

Fig 9

Expression of mgrA gene (A, n = 3), adhesion to fibrinogen in 96-well plates (B, n = 6) and clumping after 1h (C, n = 4) of S. aureus strain LAC grown in presence of increasing concentrations of biochanin A (or DMSO control) was tested. Adhesion to fibrinogen of S. aureus LAC carrying mgrA expressing complementing plasmid (D, n = 6) or with additional mutations of giant surface proteins (E, n = 6) in presence of biochanin A was also tested. *p<0.05, **p<0.01, ****p<0.0001. Data presented as mean ± SEM.