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. 2019 Jun 4;14(6):e0217270. doi: 10.1371/journal.pone.0217270

Table 3. In vitro whole-cell anti-TB activity of 7-methoxy-indolizine analogues (5a–j) against H37RV and MDR-MTB isolates.

Compound Code Anti-TB activity—MIC (μg/mL)
H37RV isolate MDR-MTB isolate*
5a 8 32
5b NA NA
5c 32 64
5d 8 NA
5e 32 NA
5f 32 NA
5g NA NA
5h NA NA
5i 8 16
5j 8 16

MIC, minimum inhibitory concentration.

*These isolates were found to be resistant to the first-line antibiotics rifampicin (1 μg/mL), and isoniazid (0.2 μg/mL).

NA: not active