Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Hypoxia induces nuclear translocation of HIF-1α in chondrocytes grown in alginate beads. Three-dimensional reconstructions of HIF-1α immunofluorescence (shown in red) in (A) normoxic cell with perinuclear HIF-1α staining and (B) hypoxic cell with intranuclear HIF-1α staining. Calibration bar = 2 μm. (C) Percentage of chondrocytes with intranuclear HIF-1α in alginate cultures in normoxia (21% O2) or hypoxia (2% O2). *p < 0.05 versus normoxia.
