Table 3.

First-degree relative enrollment and biospecimen collection, by race/ethnicity, age, personal cancer history, education, and country of birth

	Eligible relatives a n = 4,279						Enrolled relatives b n = 3,306
	Enrollment b				Biospecimen collection c		Biospecimen collection d
	n	%	OR e	95% CI	n	%	n	%	OR f	95% CI
Overall participation	3,306	77			2,774	65	2,774	84
Race/ethnicity g
Non-Hispanic whites	872	87	1.0		755	76	755	87	1.0
Hispanics	1,045	77	0.47	0.37-0.61	907	67	907	87	1.00	0.71-1.42
African Americans	807	74	0.44	0.34-0.57	660	60	660	82	0.70	0.51-0.97
Asian Americans	582	70	0.35	0.26-0.45	452	54	452	78	0.59	0.42-0.82
Chinese	204	67	0.29	0.20-0.43	144	48	144	71	0.40	0.25-0.62
Japanese	78	80	0.58	0.33-1.01	69	70	69	88	1.27	0.62-2.60
Filipinas	226	67	0.32	0.22-0.45	178	53	178	79	0.61	0.37-1.02
Others h	74	76	0.46	0.24-0.87	61	63	61	82	0.58	0.32-1.06
P value for differences by race/ethnicity i		<0.01	<0.01			<0.01		<0.01	<0.01
Proband’s age at diagnosis (years)
18-34	396	84	1.0		357	75
35-49	1,355	77	0.75	0.55-1.02	1,135	64
50-64	1,555	76	0.68	0.50-0.92	1,282	63
P value for differences by age i		<0.01	0.03			<0.01
Age at interview (years)
18-34							233	91	1.0
35-49							906	85	0.58	0.37-0.90
50-64							1,106	86	0.68	0.44-1.05
≥65							529	76	0.47	0.30-0.75
P value for differences by age i								<0.01	<0.01
Personal cancer history j
No	2,766	77	1.0		2,324	65	2,324	84	1.0
Yes	540	78	0.93	0.77-1.13	450	65	450	83	1.20	0.91-1.59
P value for differences by personal cancer history i		0.67	0.48			0.90		0.69	0.19
Education k
Some high school or less							514	86	1.0
High school graduate							586	86	0.96	0.68-1.35
Some college or other l							923	85	0.90	0.66-1.23
College graduate							733	85	0.91	0.65-1.29
P value for differences by education i								0.65	<0.01
Country of birth
U.S.-born							2,017	85	1.0
Foreign-born							756	82	0.91	0.70-1.19
P value for differences by country of birth i								0.10	0.49

^aAdult first-degree relatives: mothers, fathers, full and half-sisters, and adult daughters and sons with a prior diagnosis of breast, ovarian or childhood cancer.

^bCompleted risk factor questionnaire.

^cCompleted risk factor questionnaire and provided a blood or mouthwash sample.

^dEnrolled relatives who provided a blood or mouthwash sample.

^eOdds ratio of participation and 95% confidence interval, mutually adjusted for race/ethnicity, proband’s age at diagnosis, and personal cancer history.

^fOdds ratio of participation and 95% confidence interval, mutually adjusted for race/ethnicity, age at interview, personal cancer history, education, and country of birth.

^gFor enrolled relatives, based on self-report; for eligible relatives who did not enroll, based on proband’s self-reported race/ethnicity.

^hIncludes other Asian Americans, Pacific Islanders, Native Americans, and mixed race/ethnicity.

ⁱP value from chi square test; in multivariable models, P value from Wald test.

^jPersonal history of breast, ovarian or childhood cancer.

^kEducation was unknown for 18 relatives.

^lTechnical or vocational school.