Comparison 1. Treatment benefit of antibiotic prophylaxis versus no antibiotic prophylaxis.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Number of participants experiencing shunt infection after administration of antibiotics	11	1109	Risk Ratio (IV, Fixed, 95% CI)	0.55 [0.36, 0.84]
1.1 Intravenous administration of antibiotics	8	797	Risk Ratio (IV, Fixed, 95% CI)	0.55 [0.33, 0.90]
1.2 Intrathecal administration of antibiotics	2	202	Risk Ratio (IV, Fixed, 95% CI)	0.73 [0.28, 1.93]
1.3 Antibiotic Impregnated Catheters	1	110	Risk Ratio (IV, Fixed, 95% CI)	0.36 [0.10, 1.24]