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. 2019 Jun 4;2019(6):CD012902. doi: 10.1002/14651858.CD012902.pub2

Comparison 4. Treatment benefit of antibiotic prophylaxis for different antibiotic agents.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Number of participants experiencing shunt infection for different antibiotic agents 11 1109 Risk Ratio (IV, Random, 95% CI) 0.55 [0.36, 0.84]
1.1 Administration of penicillin 4 390 Risk Ratio (IV, Random, 95% CI) 0.59 [0.22, 1.63]
1.2 Admnistration of trimethoprim ‐ sulphamethoxazole 2 242 Risk Ratio (IV, Random, 95% CI) 0.49 [0.15, 1.61]
1.3 Administration of vancomycin 1 158 Risk Ratio (IV, Random, 95% CI) 1.03 [0.35, 3.04]
1.4 Administration of cephalosporin 2 165 Risk Ratio (IV, Random, 95% CI) 0.51 [0.18, 1.43]
1.5 Administration of gentamicin 1 44 Risk Ratio (IV, Random, 95% CI) 0.21 [0.03, 1.72]
1.6 Implantation of antibiotic‐impregnated catheters 1 110 Risk Ratio (IV, Random, 95% CI) 0.36 [0.10, 1.24]