#	Query	Results
S1	(MH “Immunologic Deficiency Syndromes+”)	71,189
S2	(MH “Human Immunodeficiency Virus+”)	6,682
S3	(immunodeficien∗ OR PIDD OR PIDDs OR PID OR PIDs OR SID OR SIDs)	29,272
S4	(HIV OR AIDS OR XLA OR CVID)	110,135
S5	(agammaglobulin#emi∗ OR agamma globulin#emi∗ OR Hypogammaglobulin#emi∗ OR Hypogamma globulin#emi∗ OR hypo gammaglobulin#emi∗ OR hypo gamma globulin#emi∗ OR hypo IgG OR hypergammaglobulin#emi∗ OR hypergamma globulin#emi∗ OR hyper gammaglobulin#emi∗ OR hyper gamma globulin#emi∗ OR Hyperimmunoglobulin∗ OR hyper immunoglobulin∗ OR hyper IgM OR HIGM OR hyper IgE OR HIES OR hyper IgD OR HIDS OR hypoimmunoglobulin#emi∗ OR hypo immunoglobulin#emi∗ OR Dysgammaglobulin#emi∗)	967
S6	((Tcell OR T cell OR Bcell OR B cell OR TBcell OR TB cell OR Adenosine deaminase OR ZAP70 OR immune OR immuno OR immunity OR immunologic∗ OR antibody OR immunoglobulin∗ OR immune globulin∗ OR gammaglobulin OR gamma globulin OR IgG OR IgA OR Leukocyte-Adhesion) N2 (deficien∗ OR defect∗ OR disorder∗))	3,887
S7	((immun∗ OR idiopathic OR purpura) N2 thrombocytopeni∗)	2,008
S8	S1 OR S2 OR S3 OR S4 OR S5 OR S6 OR S7	120,895
S9	(MH “Immunoglobulins”)	11,680
S10	(MH “Immunoglobulins, Intravenous”)	1,775
S11	(MH “Immunotherapy”)	4,714
S12	(MH “Gamma Globulins”)	139
S13	S9 OR S10 OR S11 OR S12	17,916
S14	(MH “Injections, Subcutaneous+”)	3,195
S15	(MH “Infusions, Subcutaneous”)	658
S16	(subcutaneous∗ OR “sub cutaneous” OR “sub cutaneously”)	14,850
S17	S14 OR S15 OR S16	14,938
S18	S13 AND S17	373
S19	((subcutaneous∗ OR “sub cutaneous” OR “sub cutaneously”) N6 (immunoglobulin∗ OR Ig OR IgG OR immune globulin∗ OR gammaglobulin OR gammaglobulins OR gamma globulin OR gamma globulins OR immunotherap∗ OR immune therap∗ OR Gamunex∗ OR Gammagard∗ OR Subcuvia∗ OR Endobulin∗ OR Privigen∗ OR Nordimmun∗ OR Gammaplex∗ OR Octagam∗ OR Gammanorm∗ OR KIOVIG∗))	297
S20	(SCIG OR SCIGG OR SC IG OR SC IGG OR IGSC)	33
S21	(Hizentra∗ OR IgPro20∗ OR Vivaglobin∗ OR Beriglobin∗ OR Evogam∗ OR Gammabulin∗ OR HYQVIA∗ OR IGHy OR Subgam∗)	19
S22	S18 OR S19 OR S20 OR S21	520
S23	S8 AND S22	77
S24	S23	76
S25	(MH “Economics”)	11,303
S26	(MH “Economic Aspects of Illness”)	6,876
S27	(MH “Economic Value of Life”)	521
S28	MH “Economics, Dental”	109
S29	MH “Economics, Pharmaceutical”	1,795
S30	MW “ec”	144,148
S31	(econom∗ or price or prices or pricing or priced or discount∗ or expenditure∗ or budget∗ or pharmacoeconomic∗ or pharmaco-economic∗)	221,952
S32	(MH “Costs and Cost Analysis+”)	86,622
S33	TI cost∗	40,864
S34	(cost effective∗)	29,781
S35	AB (cost∗ N2 (util∗ or efficacy∗ or benefit∗ or minimi∗ or analy∗ or saving∗ or estimate∗ or allocation or control or sharing or instrument∗ or technolog∗))	20,585
S36	(decision N1 (tree∗ or analy∗ or model∗))	5,381
S37	(markov or markow or monte carlo)	3,537
S38	(MH “Quality-Adjusted Life Years”)	2,782
S39	(QOLY or QOLYs or HRQOL or HRQOLs or QALY or QALYs or QALE or QALEs)	6,703
S40	((adjusted N1 (quality or life)) or (willing∗ N2 pay) or sensitivity analys?s)	12,555
S41	S25 OR S26 OR S27 OR S28 OR S29 OR S30 OR S31 OR S32 OR S33 OR S34 OR S35 OR S36 OR S37 OR S38 OR S39 OR S40	296,935
S42	S24 AND S41	16
S43	S24 AND Limiters – English Language	16