Table 2. TWAS analyses in ovarian cancer.
FTSEC, fallopian tube secretory epithelial cell; OSEC, ovarian surface epithelial cell; HGSOC, high-grade serous ovarian cancer.
| Site | Type | Samples | Tested genes | Tested splice variants | Significant genes | Significant splice variants | Significant splice variant genes |
|---|---|---|---|---|---|---|---|
| Breast | Normal tissue | 84 | 1984 | 5391 | 3 | 9 | 3 |
| Breast | Tumor tissue | 654 | 4465 | 21568 | 7 | 23 | 9 |
| Ovary | Normal FTSEC | 70 | 541 | - | 2 | - | - |
| Ovary | Normal OSEC | 115 | 607 | - | 0 | - | - |
| Ovary | Tumor tissue (HGSOC) | 201 | 1744 | 8759 | 7 | 18 | 8 |
| Prostate | Tumor tissue | 376 | 4414 | 17857 | 13 | 24 | 10 |