Table 1 –
Baseline Patient Characteristics by Cohort
Variable | Pre-Exposure(n = 183) | Post-Exposure(n = 179) | p-value |
---|---|---|---|
Age at Transplant (years), median (IQR) | 58 (52, 64) | 58.0 (50, 63) | 0.32 |
Male Sex | 124 (67.8%) | 130 (72.6%) | 0.31 |
Race | 0.70 | ||
White | 131 (71.6%) | 136 (76.0%) | |
Black | 33 (18.0%) | 27 (15.1%) | |
Asian | 5 (2.7%) | 6 (3.4%) | |
Other/unknown | 14 (7.7%) | 10 (5.6%) | |
Body Mass Index, median (IQR) | 27.5 (23.6, 32.6) | 26.6 (24.3, 30.7) | 0.48 |
Etiology of Liver Disease | 0.07 | ||
Hepatitis C | 75 (41.4%) | 63 (35.2%) | |
Hepatitis B | 1 (0.6%) | 8 (4.5%) | |
Alcoholic Liver Disease | 30 (16.6%) | 42 (23.5%) | |
NAFLD | 24 (13.3%) | 16 (8.9%) | |
Autoimmune | 32 (17.7%) | 32 (17.9%) | |
Other | 19 (10.5%) | 18 (10.1%) | |
MELD-Na, median (IQR) | 20 (15, 25) | 18 (12, 28) | 0.20 |
MELD Exceptions Granted | 18 (9.8%) | 41 (22.9%) | <0.001* |
Exception for Hepatocellular Carcinoma | 17 (9.3%) | 38 (21.2%) | 0.002* |
MELD-Na with Exceptions, median (IQR) | 22 (16, 27) | 23 (15, 30) | 0.22 |
Dialysis Status | 0.39 | ||
No HD | 149 (81.9%) | 153 (85.5%) | |
Peri-transplant HD | 33 (18.1%) | 26 (14.5%) | |
Transplant type | 0.08 | ||
Inpatient | 51 (27.9%) | 36 (20.1%) | |
Elective | 132 (72.1%) | 143 (79.9%) | |
Retransplant on Index Admission | 4 (2.2%) | 5 (2.8%) | 0.75 |
Total Length of Stay (days), median (IQR) | 11 (8, 19) | 9.0 (7, 17) | 0.13 |
Post-op Length of Stay (days), median (IQR) | 9 (7, 13) | 9.0 (7, 13) | 0.41 |
Weekend Discharge | 22 (12%) | 26 (14%) | 0.48 |
Index Hospitalization Disposition | 0.13 | ||
Home | 129 (70.9%) | 137 (76.5%) | |
Rehab | 48 (26.4%) | 33 (18.4%) | |
Skilled Nursing Facility/Long-term Care | 5 (2.7%) | 9 (5.0%) | |
Distance to Transplant Center (miles), median (IQR) | 30.1 (13.5, 82.4) | 33.6 (15.0, 66.3) | 0.75 |
Statistically significant at the alpha = 0.05 level
IQR = interquartile range; NAFLD = non-alcoholic fatty liver disease; MELD = model for end-stage liver disease; HD = hemodialysis