Table 3 –
Univariate and Multivariable Cox Regression Analysis: Variables Associated with 30-day and 90-day Readmission
| Univariate Analysis* |
Multivariable Analysis |
|||
|---|---|---|---|---|
| Variable | Hazard Ratio (95% CI) | p-value | Hazard Ratio (95% CI) | p-value |
| 30-Day Readmission | ||||
| Male Sex | 0.67 (0.46 – 0.96) | 0.03 | 0.66 (0.45 – 0.97) | 0.03 |
| Transplant MELD-Na (per 5 points) | 1.09 (0.99 – 1.21) | 0.09 | ∙ | ∙ |
| Peri-transplant Dialysis | 2.24 (1.50 – 3.35) | <0.001 | 1.70 (1.13 – 2.58) | 0.01 |
| Retransplant | 2.23 (0.91 – 5.47) | 0.08 | 10.21 (3.39 – 30.75) | <0.001 |
| Total Length of Stay (per day) | 1.01 (1.00 – 1.01) | 0.05 | ∙ | ∙ |
| Index Hospitalization Disposition (ref = Home) | ||||
| Rehab | 2.01 (1.37 – 2.96) | <0.001 | ∙ | ∙ |
| Skilled Nursing Facility/Long-term Care | 1.22 (0.49 – 3.01) | 0.67 | ∙ | ∙ |
| Exposure Arm | 0.61 (0.42 – 0.88) | 0.008 | 0.60 (0.39 – 0.90) | 0.02 |
| Number of Clinic Visits | 0.60 (0.51 – 0.71) | 0.000 | 0.56 (0.47 – 0.66) | <0.001 |
| Number of Phone Encounters | 1.03 (1.00 – 1.07) | 0.06 | 1.08 (1.04 – 1.13) | <0.001 |
| 90-Day Readmission | ||||
| Male Sex | 0.63 (0.46 – 0.88) | 0.006 | 0.63 (0.45 – 0.88) | 0.007 |
| MELD exception granted | 0.62 (0.38 – 1.02) | 0.06 | ∙ | ∙ |
| Peri-transplant Dialysis | 1.87 (1.28 – 2.72) | 0.001 | ∙ | ∙ |
| Total Length of Stay (per day) | 1.01 (1.00 – 1.01) | 0.09 | ∙ | ∙ |
| Index Hospitalization Disposition (ref = Home) | ||||
| Rehab | 1.75 (1.24 – 2.49) | 0.002 | 4.62 (1.80 – 11.9) | 0.02 |
| Skilled Nursing Facility/Long-term Care | 0.90 (0.37 – 2.21) | 0.82 | 0.90 (0.18 – 4.49) | 0.90 |
| Disposition*Clinic Visit Interaction (ref = Home) | ||||
| Rehab | 0.81 (0.68 – 0.97) | 0.02 | 0.83 (0.72 – 0.97) | 0.02 |
| Skilled Nursing Facility/Long-term Care | 0.64 (0.44 – 0.93) | 0.02 | 0.85 (0.59 – 1.21) | 0.36 |
| Exposure Arm | 0.69 (0.59 – 0.95) | 0.02 | 0.49 (0.34 – 0.71) | <0.001 |
| Number of Clinic Visits | 0.91 (0.83 – 1.00) | 0.06 | 0.92 (0.83 – 1.02) | 0.11 |
| Number of Phone Encounters | 1.03 (1.01 – 1.04) | <0.001 | 1.06 (1.04 – 1.08) | <0.001 |
*
The following variables were not statistically significant at the alpha = 0.10 level: age, race, body mass index, etiology of liver disease, hepatitis C-related liver disease (binary), elective transplant, post-operative length of stay, weekend discharge, distance to transplant center, MELD exception granted (30-day model), and transplant MELD-Na (90-day model)