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. Author manuscript; available in PMC: 2019 Jun 4.
Published in final edited form as: Nat Protoc. 2018 Jan 11;13(1):307–323. doi: 10.1038/nprot.2017.131

Figure 5. Anticipated Screening Results.

Figure 5.

(a) Lorenz curves illustrating the abundance disparity in four CRISPR library (orange) and four Passage 3 (blue) samples after Next-Generation Sequencing. (b) Correlation between phenotype scores of two biological replicates of a CRISPR screen for T. gondii genes that confer fitness when parasites are grown in HFF cells. Perfect correlation is indicated by a diagonal line. (c) Phenotype scores associated with 40 known dispensable and 40 known essential genes after a screen for fitness-conferring genes.