. Author manuscript; available in PMC: 2020 Jul 1.

Published in final edited form as: Int J Radiat Oncol Biol Phys. 2019 Feb 23;104(3):513–521. doi: 10.1016/j.ijrobp.2019.02.034

Table 1.

Preparative Regimens

Preparative Regimen	Treatment	Route	Dose	Days	Important Notes
Desired preparative regiment administration	TBI		200cGy BID	Day −8, −7, &−6	May deliver 1200cGy over 3 days per center preference
	Thiotepa	IV	5 mg/kg/day	Day −5&−4
	Cyclophosphamide	IV	60 mg/kg/day	Day −3&−2
	Rest			Day −1
	Infusion of allogeneic HSCT			Day 0
Allowed Preparative Regimen Administration Variant 1. TBI/Cy/VP-16 Administration	TBI		200cGy BID	Day −8, −7, &−5	May deliver 1200cGy over 3 days per center preference
	Etoposide	IV	1500 mg/m²	Day −4
	Cyclophosphamide	IV	60 mg/kg/day	Day −3&−2
	Rest			Day −1
	Infusion of allogeneic HSCT			Day 0
Higher Dose TBI/Cy Administration	TBI		165cGy BID	Day −7, −6, −5&−4	Total dose must be1320cGy
	Cyclophosphamide	IV	60 mg/kg/day	Day −3&−2
	Rest			Day −1
	Infusion of allogeneic HSCT			Day 0