Table 4.
Multiviariable Analysis of Survival Outcome
Parameter | Level | Reference level | Hazard Ratio | 95%CI for HR | P-value (compare to the reference level) | P-value (variable effect) | |
---|---|---|---|---|---|---|---|
Dose | >=800 | <800 | 1.855 | 1.021 | 3.372 | 0.0426 | 0.0426 |
risk_donor | HR_CR2 Cord | VHR_CR1 Other | 1.342 | 0.562 | 3.204 | 0.5076 | 0.0074 |
HR_CR2 Matched | VHR_CR1 Other | 1.069 | 0.455 | 2.508 | 0.8787 | ||
HR_CR2 Other | VHR_CR1 Other | 0.955 | 0.393 | 2.317 | 0.9186 | ||
IR_CR2 Matched | VHR_CR1 Other | 0.240 | 0.065 | 0.892 | 0.0331 | ||
VHR_CR1 Matched | VHR_CR1 Other | 0.247 | 0.082 | 0.740 | 0.0125 |
Multivariate survival model include dose level, fieldname, position, disease risk group and donor type,
TacroMTX versus MacroMTX and Sirolimus treatment, MRD at 0.10% level.
Abbreviations: PFS-Progression-free survival, OS-overall survival; HR-high risk; IR-intermediate risk; CR-complete remission; VHR-very high risk;